Gene: ABCB10

Alternate names for this Gene: EST20237|M-ABC2|MTABC2

Gene Summary: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The function of this mitochondrial protein is unknown.

Gene is located in Chromosome: 1

Location in Chromosome : 1q42.13

Description of this Gene: ATP binding cassette subfamily B member 10

Type of Gene: protein-coding

rs11810108 in ABCB10 gene and Blood Protein Measurement PMID 30111768 2018 Genome-wide mapping of plasma protein QTLs identifies putatively causal genes and pathways for cardiovascular disease.

rs348330 in ABCB10 gene and Diabetes Mellitus, Non-Insulin-Dependent PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.

PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs2145394 in ABCB10 gene and Eosinophil count procedure PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.