Gene: ADAMTS19

Alternate names for this Gene: -

Gene Summary: This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene has high sequence similarity to the protein encoded by ADAMTS16, another family member.

Gene is located in Chromosome: 5

Location in Chromosome : 5q23.3

Description of this Gene: ADAM metallopeptidase with thrombospondin type 1 motif 19

Type of Gene: protein-coding

rs17163154 in ADAMTS19 gene and Adolescent idiopathic scoliosis PMID 30019117 2018 The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.

rs246242 in ADAMTS19 gene and Body Height PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs7719477 in ADAMTS19 gene and Eosinophil count procedure PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs246246 in ADAMTS19 gene and Ovarian Failure, Premature PMID 19508998 2009 Genome-wide association study in premature ovarian failure patients suggests ADAMTS19 as a possible candidate gene.

rs13436218 in ADAMTS19 gene and Psychosexual dysfunction PMID 22445761 2012 Genome-wide association study of SSRI/SNRI-induced sexual dysfunction in a Japanese cohort with major depression.

rs246246 in ADAMTS19 gene and Red Blood Cell Count measurement PMID 19862010 2009 Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.

rs17163154 in ADAMTS19 gene and SCOLIOSIS, ISOLATED, SUSCEPTIBILITY TO, 3 PMID 30019117 2018 The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.

rs13436218 in ADAMTS19 gene and Sexual Dysfunction PMID 22445761 2012 Genome-wide association study of SSRI/SNRI-induced sexual dysfunction in a Japanese cohort with major depression.