Gene: ADORA2B

Alternate names for this Gene: ADORA2

Gene Summary: This gene encodes an adenosine receptor that is a member of the G protein-coupled receptor superfamily. This integral membrane protein stimulates adenylate cyclase activity in the presence of adenosine. This protein also interacts with netrin-1, which is involved in axon elongation. The gene is located near the Smith-Magenis syndrome region on chromosome 17.

Gene is located in Chromosome: 17

Location in Chromosome : 17p12

Description of this Gene: adenosine A2b receptor

Type of Gene: protein-coding

rs2324082 in ADORA2B gene and Waist-Hip Ratio PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.