Gene: AFF4

Alternate names for this Gene: AF5Q31|CHOPS|MCEF

Gene Summary: The protein encoded by this gene belongs to the AF4 family of transcription factors involved in leukemia. It is a component of the positive transcription elongation factor b (P-TEFb) complex. A chromosomal translocation involving this gene and MLL gene on chromosome 11 is found in infant acute lymphoblastic leukemia with ins(5;11)(q31;q31q23).

Gene is located in Chromosome: 5

Location in Chromosome : 5q31.1

Description of this Gene: AF4/FMR2 family member 4

Type of Gene: protein-coding

Gene: LEAP2

Alternate names for this Gene: LEAP-2

Gene Summary: This gene encodes a cysteine-rich cationic antimicrobial peptide that is expressed predominantly in the liver. The mature peptide has activity against gram-positive bacteria and yeasts.

Gene is located in Chromosome: 5

Location in Chromosome : 5q31.1

Description of this Gene: liver enriched antimicrobial peptide 2

Type of Gene: protein-coding