Gene: AGAP2

Alternate names for this Gene: CENTG1|GGAP2|PIKE

Gene Summary: The protein encoded by this gene belongs to the centaurin gamma-like family. It mediates anti-apoptotic effects of nerve growth factor by activating nuclear phosphoinositide 3-kinase. It is overexpressed in cancer cells, and promotes cancer cell invasion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene is located in Chromosome: 12

Location in Chromosome : 12q14.1

Description of this Gene: ArfGAP with GTPase domain, ankyrin repeat and PH domain 2

Type of Gene: protein-coding