Gene: ARL3
Alternate names for this Gene: ARFL3|JBTS35|RP83
Gene Summary: ADP-ribosylation factor-like 3 is a member of the ADP-ribosylation factor family of GTP-binding proteins. ARL3 binds guanine nucleotides but lacks ADP-ribosylation factor activity.
Gene is located in Chromosome: 10
Location in Chromosome : 10q24.32
Description of this Gene: ADP ribosylation factor like GTPase 3
Type of Gene: protein-coding
rs776901858 in
ARL3 gene and
JOUBERT SYNDROME 35
PMID 30269812 2018 ARL3 Mutations Cause Joubert Syndrome by Disrupting Ciliary Protein Composition.
rs4919669 in
ARL3 gene and
Mean blood pressure
PMID 30487518 2018 Interethnic analyses of blood pressure loci in populations of East Asian and European descent.
PMID 28348047 2017 Genome-Wide Association Study Meta-Analysis of Long-Term Average Blood Pressure in East Asians.
rs10883765 in
ARL3 gene and
Schizophrenia
PMID 27922604 2017 Common variants on 2p16.1, 6p22.1 and 10q24.32 are associated with schizophrenia in Han Chinese population.
rs4919669 in
ARL3 gene and
Systolic Pressure
PMID 28348047 2017 We identified 1 novel <i>ARL3</i> variant, rs4919669 at 10q24.32, influencing LTA systolic BP (stage-1 <i>P</i>=5.03×10<sup>-</sup><sup>8</sup>, stage-2 <i>P</i>=8.64×10<sup>-</sup><sup>3</sup>, joint <i>P</i>=2.63×10<sup>-</sup><sup>8</sup>) and mean arterial pressure (stage-1 <i>P</i>=3.59×10<sup>-</sup><sup>9</sup>, stage-2 <i>P</i>=2.35×10<sup>-</sup><sup>2</sup>, joint <i>P</i>=2.64×10<sup>-</sup><sup>8</sup>).
PMID 30487518 2018 Interethnic analyses of blood pressure loci in populations of East Asian and European descent.