Gene: BANF1

Alternate names for this Gene: BAF|BCRP1|D14S1460|NGPS

Gene Summary: The protein encoded by this gene was first identified by its ability to protect retroviruses from intramolecular integration and therefore promote intermolecular integration into the host cell genome. The protein forms a homodimer which localizes to both the nucleus and cytoplasm and is specifically associated with chromosomes during mitosis. This protein binds to double stranded DNA in a non-specific manner and also binds to LEM-domain containing proteins of the nuclear envelope. This protein is thought to facilitate nuclear reassembly by binding with both DNA and inner nuclear membrane proteins and thereby recruit chromatin to the nuclear periphery. Alternative splicing results in multiple transcript variants encoding the same protein.

Gene is located in Chromosome: 11

Location in Chromosome : 11q13.1

Description of this Gene: BAF nuclear assembly factor 1

Type of Gene: protein-coding

Gene: EIF1AD

Alternate names for this Gene: OBELIX|haponin

Gene Summary:

Gene is located in Chromosome: 11

Location in Chromosome : 11q13.1

Description of this Gene: eukaryotic translation initiation factor 1A domain containing

Type of Gene: protein-coding

rs3825068 in BANF1;EIF1AD gene and Blood Protein Measurement PMID 29875488 2018 Genomic atlas of the human plasma proteome.

rs387906871 in BANF1;EIF1AD gene and Nestor Guillermo progeria syndrome PMID 21549337 2011 Exome sequencing and functional analysis identifies BANF1 mutation as the cause of a hereditary progeroid syndrome.