Gene: BIRC2

Alternate names for this Gene: API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1

Gene Summary: The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene is located in Chromosome: 11

Location in Chromosome : 11q22.2

Description of this Gene: baculoviral IAP repeat containing 2

Type of Gene: protein-coding