Gene: BOK

Alternate names for this Gene: BCL2L9|BOKL

Gene Summary: The protein encoded by this gene belongs to the BCL2 family, members of which form homo- or heterodimers, and act as anti- or proapoptotic regulators that are involved in a wide variety of cellular processes. Studies in rat show that this protein has restricted expression in reproductive tissues, interacts strongly with some antiapoptotic BCL2 proteins, not at all with proapoptotic BCL2 proteins, and induces apoptosis in transfected cells. Thus, this protein represents a proapoptotic member of the BCL2 family.

Gene is located in Chromosome: 2

Location in Chromosome : 2q37.3

Description of this Gene: BCL2 family apoptosis regulator BOK

Type of Gene: protein-coding

rs5839768 in BOK gene and Body Height PMID 31562340 2019 Characterizing rare and low-frequency height-associated variants in the Japanese population.

PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.