Gene: C14orf39

Alternate names for this Gene: Six6os1

Gene Summary:

Gene is located in Chromosome: 14

Location in Chromosome : 14q23.1

Description of this Gene: chromosome 14 open reading frame 39

Type of Gene: protein-coding

Gene: SIX6

Alternate names for this Gene: MCOPCT2|ODRMD|OPTX2|Six9

Gene Summary: The protein encoded by this gene is a homeobox protein that is similar to the Drosophila 'sine oculis' gene product. This gene is found in a cluster of related genes on chromosome 14 and is thought to be involved in eye development. Defects in this gene are a cause of isolated microphthalmia with cataract type 2 (MCOPCT2).

Gene is located in Chromosome: 14

Location in Chromosome : 14q23.1

Description of this Gene: SIX homeobox 6

Type of Gene: protein-coding

rs33912345 in C14orf39;SIX6 gene and Body Height PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs33912345 in C14orf39;SIX6 gene and Glaucoma, Open-Angle PMID 26752265 2016 Genome-wide association analysis identifies TXNRD2, ATXN2 and FOXC1 as susceptibility loci for primary open-angle glaucoma.