Gene: C1orf112

Alternate names for this Gene: -

Gene Summary:

Gene is located in Chromosome: 1

Location in Chromosome : 1q24.2

Description of this Gene: chromosome 1 open reading frame 112

Type of Gene: protein-coding

Gene: SELE

Alternate names for this Gene: CD62E|ELAM|ELAM1|ESEL|LECAM2

Gene Summary: The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis.

Gene is located in Chromosome: 1

Location in Chromosome : 1q24.2

Description of this Gene: selectin E

Type of Gene: protein-coding

rs4265482 in C1orf112;SELE gene and Blood Protein Measurement PMID 30072576 2018 Co-regulatory networks of human serum proteins link genetics to disease.