Gene: CADM3

Alternate names for this Gene: BIgR|IGSF4B|NECL1|Necl-1|TSLL1|synCAM3

Gene Summary: The protein encoded by this gene is a calcium-independent cell-cell adhesion protein that can form homodimers or heterodimers with other nectin proteins. The encoded protein has both homophilic and heterophilic cell-cell adhesion activity. This gene is reported to be a tumor suppressor gene.

Gene is located in Chromosome: 1

Location in Chromosome : 1q23.2

Description of this Gene: cell adhesion molecule 3

Type of Gene: protein-coding

rs1474747 in CADM3 gene and C-reactive protein measurement PMID 22291609 2012 A genome-wide association scan on the levels of markers of inflammation in Sardinians reveals associations that underpin its complex regulation.

rs2253837 in CADM3 gene and mathematical ability PMID 30038396 2018 Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.