Gene: CALCOCO2

Alternate names for this Gene: NDP52

Gene Summary: This gene encodes a coiled-coil domain-containing protein. The encoded protein functions as a receptor for ubiquitin-coated bacteria and plays an important role in innate immunity by mediating macroautophagy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene is located in Chromosome: 17

Location in Chromosome : 17q21.32

Description of this Gene: calcium binding and coiled-coil domain 2

Type of Gene: protein-coding

rs550510 in CALCOCO2 gene and Blood Protein Measurement PMID 30072576 2018 Co-regulatory networks of human serum proteins link genetics to disease.

rs10278 in CALCOCO2 gene and Diabetes Mellitus, Non-Insulin-Dependent PMID 29632382 2018 Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.