Gene: CCDC6

Alternate names for this Gene: D10S170|H4|PTC|TPC|TST1

Gene Summary: This gene encodes a coiled-coil domain-containing protein. The encoded protein is ubiquitously expressed and may function as a tumor suppressor. A chromosomal rearrangement resulting in the expression of a fusion gene containing a portion of this gene and the intracellular kinase-encoding domain of the ret proto-oncogene is the cause of thyroid papillary carcinoma.

Gene is located in Chromosome: 10

Location in Chromosome : 10q21.2

Description of this Gene: coiled-coil domain containing 6

Type of Gene: protein-coding

rs16914105 in CCDC6 gene and Leukemia, Myelocytic, Acute PMID 27903959 2017 Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.

rs1177701 in CCDC6 gene and Systolic Pressure PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

PMID 27841878 2017 Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.