Gene: CCL19

Alternate names for this Gene: CKb11|ELC|MIP-3b|MIP3B|SCYA19

Gene Summary: This antimicrobial gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene may play a role in normal lymphocyte recirculation and homing. It also plays an important role in trafficking of T cells in thymus, and in T cell and B cell migration to secondary lymphoid organs. It specifically binds to chemokine receptor CCR7.

Gene is located in Chromosome: 9

Location in Chromosome : 9p13.3

Description of this Gene: C-C motif chemokine ligand 19

Type of Gene: protein-coding

rs3176813 in CCL19 gene and Leukemia, Myelocytic, Acute PMID 27903959 2017 Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.