Gene: CCN3

Alternate names for this Gene: IBP-9|IGFBP-9|IGFBP9|NOV|NOVh

Gene Summary: The protein encoded by this gene is a small secreted cysteine-rich protein and a member of the CCN family of regulatory proteins. CNN family proteins associate with the extracellular matrix and play an important role in cardiovascular and skeletal development, fibrosis and cancer development.

Gene is located in Chromosome: 8

Location in Chromosome : 8q24.12

Description of this Gene: cellular communication network factor 3

Type of Gene: protein-coding

rs2071518 in CCN3 gene and Blood Pressure PMID 21909110 2011 Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure.

rs17791208 in CCN3 gene and Blood Protein Measurement PMID 30072576 2018 Co-regulatory networks of human serum proteins link genetics to disease.

rs2071518 in CCN3 gene and Diastolic blood pressure PMID 27841878 2017 Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.

rs1381335 in CCN3 gene and Diverticular Diseases PMID 30177863 2018 Genome-wide association analyses identify 39 new susceptibility loci for diverticular disease.