Gene: CDC14B

Alternate names for this Gene: CDC14B3|Cdc14B1|Cdc14B2|hCDC14B

Gene Summary: The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms.

Gene is located in Chromosome: 9

Location in Chromosome : 9q22.32-q22.33

Description of this Gene: cell division cycle 14B

Type of Gene: protein-coding

Gene: HABP4

Alternate names for this Gene: IHABP-4|IHABP4|Ki-1/57|SERBP1L

Gene Summary:

Gene is located in Chromosome: 9

Location in Chromosome : 9q22.32

Description of this Gene: hyaluronan binding protein 4

Type of Gene: protein-coding

rs6477493 in CDC14B;HABP4 gene and Intelligence PMID 29186694 2017 Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets.

PMID 29326435 2019 A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.

rs6477493 in CDC14B;HABP4 gene and mathematical ability PMID 30038396 2018 Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.