Gene: CDC14B

Alternate names for this Gene: CDC14B3|Cdc14B1|Cdc14B2|hCDC14B

Gene Summary: The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms.

Gene is located in Chromosome: 9

Location in Chromosome : 9q22.32-q22.33

Description of this Gene: cell division cycle 14B

Type of Gene: protein-coding

rs141760764 in CDC14B gene and Body Height PMID 31562340 2019 Characterizing rare and low-frequency height-associated variants in the Japanese population.

rs10820741 in CDC14B gene and mathematical ability PMID 30038396 2018 Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.