Gene: CDON

Alternate names for this Gene: CDO|CDON1|HPE11|ORCAM

Gene Summary: This gene encodes a cell surface receptor that is a member of the immunoglobulin superfamily. The encoded protein contains three fibronectin type III domains and five immunoglobulin-like C2-type domains. This protein is a member of a cell-surface receptor complex that mediates cell-cell interactions between muscle precursor cells and positively regulates myogenesis.

Gene is located in Chromosome: 11

Location in Chromosome : 11q24.2

Description of this Gene: cell adhesion associated, oncogene regulated

Type of Gene: protein-coding

rs562022020 in CDON gene and Blood Protein Measurement PMID 29875488 2018 Genomic atlas of the human plasma proteome.

PMID 30072576 2018 Co-regulatory networks of human serum proteins link genetics to disease.

rs139323558 in CDON gene and HOLOPROSENCEPHALY 11 PMID 21802063 2011 Mutations in CDON, encoding a hedgehog receptor, result in holoprosencephaly and defective interactions with other hedgehog receptors.

rs183951714 in CDON gene and Kidney Failure, Chronic PMID 31178898 2019 Genetics of Chronic Kidney Disease Stages Across Ancestries: The PAGE Study.