Gene: CHST12

Alternate names for this Gene: C4S-2|C4ST-2|C4ST2

Gene Summary: The protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin and desulfated dermatan sulfate. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage, and is distributed on the surfaces of many cells and extracellular matrices. Alternatively spliced transcript variants differing only in their 5' UTRs have been found for this gene.

Gene is located in Chromosome: 7

Location in Chromosome : 7p22.3

Description of this Gene: carbohydrate sulfotransferase 12

Type of Gene: protein-coding

rs2969076 in CHST12 gene and Blood Protein Measurement PMID 30072576 2018 Co-regulatory networks of human serum proteins link genetics to disease.