Gene: CMTM1

Alternate names for this Gene: CKLFH|CKLFH1|CKLFSF1

Gene Summary: This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and the transmembrane 4 superfamilies of signaling molecules. The protein encoded by this gene may play an important role in testicular development. Alternatively spliced transcript variants encoding different isoforms have been identified. Naturally occurring read-through transcription occurs between this locus and the neighboring locus CKLF (chemokine-like factor).

Gene is located in Chromosome: 16

Location in Chromosome : 16q21

Description of this Gene: CKLF like MARVEL transmembrane domain containing 1

Type of Gene: protein-coding

Gene: CKLF-CMTM1

Alternate names for this Gene: -

Gene Summary: This locus represents naturally occurring read-through transcription between the neighboring CKLF (chemokine-like factor) and CMTM1 (CKLF-like MARVEL transmembrane domain containing 1) genes on chromosome 16. The read-through transcript produces a fusion protein that shares sequence identity with each individual gene product.

Gene is located in Chromosome: 16

Location in Chromosome : 16q21

Description of this Gene: CKLF-CMTM1 readthrough

Type of Gene: protein-coding

Gene: CKLF

Alternate names for this Gene: C32|CKLF1|CKLF2|CKLF3|CKLF4|HSPC224|UCK-1

Gene Summary: The product of this gene is a cytokine. Cytokines are small proteins that have an essential role in the immune and inflammatory responses. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 16. The protein encoded by this gene is a potent chemoattractant for neutrophils, monocytes and lymphocytes. It also can stimulate the proliferation of skeletal muscle cells. This protein may play important roles in inflammation and in the regeneration of skeletal muscle. Alternatively spliced transcript variants encoding different isoforms have been identified. Naturally occurring read-through transcription occurs between this locus and the neighboring locus CMTM1 (CKLF-like MARVEL transmembrane domain containing 1).

Gene is located in Chromosome: 16

Location in Chromosome : 16q21

Description of this Gene: chemokine like factor

Type of Gene: protein-coding

rs16956732 in CMTM1;CKLF-CMTM1;CKLF gene and Schizophrenia PMID 21926974 2011 Genome-wide association study identifies five new schizophrenia loci.