Gene: CNOT1

Alternate names for this Gene: AD-005|CDC39|HPE12|NOT1|NOT1H|VIBOS

Gene Summary:

Gene is located in Chromosome: 16

Location in Chromosome : 16q21

Description of this Gene: CCR4-NOT transcription complex subunit 1

Type of Gene: protein-coding

rs7184114 in CNOT1 gene and Child Development Disorders, Pervasive PMID 28540026 2017 Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia.

rs246196 in CNOT1 gene and QT interval feature (observable entity) PMID 31217584 2019 Genetic analyses of diverse populations improves discovery for complex traits.

PMID 24952745 2014 Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization.

PMID 22726844 2012 A common variant in SLC8A1 is associated with the duration of the electrocardiographic QT interval.

PMID 20062063 2010 Several common variants modulate heart rate, PR interval and QRS duration.

PMID 19305408 2009 Common variants at ten loci influence QT interval duration in the QTGEN Study.

PMID 19305409 2009 Common variants at ten loci modulate the QT interval duration in the QTSCD Study.

PMID 30679814 2019 Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits.

rs11867022 in CNOT1 gene and Red Blood Cell Count measurement PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs7184114 in CNOT1 gene and Schizophrenia PMID 28540026 2017 Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia.