Gene: CNOT6

Alternate names for this Gene: CCR4|Ccr4a

Gene Summary: This gene encodes the catalytic component of the CCR4-NOT core transcriptional regulation complex. The encoded protein has a 3'-5' RNase activity and prefers polyadenylated substrates. The CCR4-NOT complex plays a role in many cellular processes, including miRNA-mediated repression, mRNA degradation, and transcriptional regulation.

Gene is located in Chromosome: 5

Location in Chromosome : 5q35.3

Description of this Gene: CCR4-NOT transcription complex subunit 6

Type of Gene: protein-coding

rs78183295 in CNOT6 gene and Blood Protein Measurement PMID 30072576 2018 Co-regulatory networks of human serum proteins link genetics to disease.