Gene: CORO7-PAM16

Alternate names for this Gene: CORO7|Coronin-7|Crn7

Gene Summary: This locus represents naturally occurring read-through transcription between the neighboring CORO7 (coronin 7) and PAM16 (presequence translocase-associated motor 16) genes on chromosome 16. The read-through transcript encodes a fusion protein that shares sequence identity with each individual gene product.

Gene is located in Chromosome: 16

Location in Chromosome : 16p13.3

Description of this Gene: CORO7-PAM16 readthrough

Type of Gene: protein-coding

Gene: CORO7

Alternate names for this Gene: 0610011B16Rik|CRN7|POD1

Gene Summary: This gene encodes a member of the coronin protein family. However, unlike other coronin proteins, it is not an actin-binding protein but rather functions as an F-actin regulator directing anterograde Golgi to endosome transport. The encoded protein has two tandem WD-40 domain repeats and localizes to the trans-Golgi network. The protein undergoes K33-linked polyubiquitination via an E3 ligase complex. It is thought to play an essential role in maintenance of Golgi apparatus morphology. Alternative splicing results in multiple transcripts variants; some of which form read-through transcripts with a neighboring gene.

Gene is located in Chromosome: 16

Location in Chromosome : 16p13.3

Description of this Gene: coronin 7

Type of Gene: protein-coding