Gene: CRIM1

Alternate names for this Gene: CRIM-1|S52

Gene Summary: This gene encodes a transmembrane protein containing six cysteine-rich repeat domains and an insulin-like growth factor-binding domain. The encoded protein may play a role in tissue development though interactions with members of the transforming growth factor beta family, such as bone morphogenetic proteins.

Gene is located in Chromosome: 2

Location in Chromosome : 2p22.2

Description of this Gene: cysteine rich transmembrane BMP regulator 1

Type of Gene: protein-coding

Gene: FEZ2

Alternate names for this Gene: HUM3CL

Gene Summary: This gene is an ortholog of the C. elegans unc-76 gene, which is necessary for normal axonal bundling and elongation within axon bundles. Other orthologs include the rat gene that encodes zygin II, which can bind to synaptotagmin.

Gene is located in Chromosome: 2

Location in Chromosome : 2p22.2

Description of this Gene: fasciculation and elongation protein zeta 2

Type of Gene: protein-coding

rs848602 in CRIM1;FEZ2 gene and Body Height PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

PMID 31562340 2019 Characterizing rare and low-frequency height-associated variants in the Japanese population.