Gene: CRTAM

Alternate names for this Gene: CD355

Gene Summary: The CRTAM gene is upregulated in CD4 (see MIM 186940)-positive and CD8 (see CD8A; MIM 186910)-positive T cells and encodes a type I transmembrane protein with V and C1-like Ig domains (Yeh et al., 2008 [PubMed 18329370]).[supplied by OMIM, Feb 2009].

Gene is located in Chromosome: 11

Location in Chromosome : 11q24.1

Description of this Gene: cytotoxic and regulatory T cell molecule

Type of Gene: protein-coding

rs7942122 in CRTAM gene and Age at menarche PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs2370794 in CRTAM gene and Blood Protein Measurement PMID 30072576 2018 Co-regulatory networks of human serum proteins link genetics to disease.

rs17338032 in CRTAM gene and Malignant mesothelioma PMID 23827383 2013 A genome-wide association study for malignant mesothelioma risk.

rs3134425 in CRTAM gene and Small cell carcinoma of lung PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.