Gene: CTSZ

Alternate names for this Gene: CTSX

Gene Summary: The protein encoded by this gene is a lysosomal cysteine proteinase and member of the peptidase C1 family. It exhibits both carboxy-monopeptidase and carboxy-dipeptidase activities. The encoded protein has also been known as cathepsin X and cathepsin P. This gene is expressed ubiquitously in cancer cell lines and primary tumors and, like other members of this family, may be involved in tumorigenesis.

Gene is located in Chromosome: 20

Location in Chromosome : 20q13.32

Description of this Gene: cathepsin Z

Type of Gene: protein-coding

rs199825459 in CTSZ gene and Blood Protein Measurement PMID 29875488 2018 Genomic atlas of the human plasma proteome.

rs571971615 in CTSZ gene and Platelet Component Distribution Width Measurement PMID 27863252 2016 The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.