Gene: DLEU1

Alternate names for this Gene: BCMS|BCMS1|DLB1|DLEU2|LEU1|LEU2|LINC00021|NCRNA00021|XTP6

Gene Summary:

Gene is located in Chromosome: 13

Location in Chromosome : 13q14.2-q14.3

Description of this Gene: deleted in lymphocytic leukemia 1

Type of Gene: ncRNA

Gene: DLEU2

Alternate names for this Gene: ALT1|BCMSUN|DLB2|LEU2|LINC00022|MIR15AHG|NCRNA00022|RFP2|RFP2OS|TRIM13OS

Gene Summary: This locus represents a microRNA host gene and also produces long alternatively spliced non-coding RNAs. This genome region was observed to be deleted or epigenetically suppressed in leukemia, and was implicated as a negative regulator of cell proliferation. However, an alternative transcript produced at this locus was also found to promote progression through the cell cycle via angiotensin I converting enzyme 2 and cyclin D1.

Gene is located in Chromosome: 13

Location in Chromosome : 13q14.2

Description of this Gene: deleted in lymphocytic leukemia 2

Type of Gene: ncRNA

rs41284816 in DLEU1;DLEU2 gene and Body Height PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs2066590 in DLEU1;DLEU2 gene and Eosinophil count procedure PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs41284816 in DLEU1;DLEU2 gene and Glomerular Filtration Rate PMID 31152163 2019 A catalog of genetic loci associated with kidney function from analyses of a million individuals.