Gene: DOK2

Alternate names for this Gene: p56DOK|p56dok-2

Gene Summary: The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells.

Gene is located in Chromosome: 8

Location in Chromosome : 8p21.3

Description of this Gene: docking protein 2

Type of Gene: protein-coding

rs899428 in DOK2 gene and Body Height PMID 31564439 2019 Harmonizing Genetic Ancestry and Self-identified Race/Ethnicity in Genome-wide Association Studies.

rs34215892 in DOK2 gene and Eosinophil count procedure PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.