Gene: DPP7

Alternate names for this Gene: DPP2|DPPII|QPP

Gene Summary: The protein encoded by this gene is a post-proline cleaving aminopeptidase expressed in quiescent lymphocytes. The resting lymphocytes are maintained through suppression of apoptosis, a state which is disrupted by inhibition of this novel serine protease. The enzyme has strong sequence homology with prolylcarboxypeptidase and is active at both acidic and neutral pH.

Gene is located in Chromosome: 9

Location in Chromosome : 9q34.3

Description of this Gene: dipeptidyl peptidase 7

Type of Gene: protein-coding

rs10747049 in DPP7 gene and Blood Protein Measurement PMID 29875488 2018 Genomic atlas of the human plasma proteome.

rs192111487 in DPP7 gene and Waist-Hip Ratio PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.