Gene: EFCAB6

Alternate names for this Gene: DJBP|HSCBCIP1|dJ185D5.1

Gene Summary: This gene encodes a protein which directly binds the oncogene DJ-1 and androgen receptor to form a ternary complex in cells. This binding protein recruits histone-deacetylase complexes in order to repress transcription activity of androgen receptor. This protein may also play a role in spermatogenesis and fertilization. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene is located in Chromosome: 22

Location in Chromosome : 22q13.2-q13.31

Description of this Gene: EF-hand calcium binding domain 6

Type of Gene: protein-coding

rs12627753 in EFCAB6 gene and mathematical ability PMID 30038396 2018 Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.