Gene: EME2

Alternate names for this Gene: SLX2B|gs125

Gene Summary: EME2 forms a heterodimer with MUS81 (MIM 606591) that functions as an XPF (MIM 278760)-type flap/fork endonuclease in DNA repair (Ciccia et al., 2007 [PubMed 17289582]).[supplied by OMIM, Mar 2008]. ##Evidence-Data-START## Transcript exon combination :: EF452422.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2145893 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END##

Gene is located in Chromosome: 16

Location in Chromosome : 16p13.3

Description of this Gene: essential meiotic structure-specific endonuclease subunit 2

Type of Gene: protein-coding

Gene: SPSB3

Alternate names for this Gene: C16orf31|SSB3

Gene Summary:

Gene is located in Chromosome: 16

Location in Chromosome : 16p13.3

Description of this Gene: splA/ryanodine receptor domain and SOCS box containing 3

Type of Gene: protein-coding

rs35816944 in EME2;SPSB3 gene and Body Height PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.