Gene: ENPP7

Alternate names for this Gene: ALK-SMase|E-NPP 7|NPP-7|NPP7

Gene Summary: The protein encoded by this gene is an intestinal alkaline sphingomyelin phosphodiesterase that converts sphingomyelin to ceramide and phosphocholine. The encoded protein is anchored in the cell membrane, and it may function to protect the intestinal mucosa from inflammation and tumorigenesis. This protein is glycosylated and also exhibits lysophosphatidylcholine hydrolase activity.

Gene is located in Chromosome: 17

Location in Chromosome : 17q25.3

Description of this Gene: ectonucleotide pyrophosphatase/phosphodiesterase 7

Type of Gene: protein-coding

rs112460278 in ENPP7 gene and Blood Protein Measurement PMID 29875488 2018 Genomic atlas of the human plasma proteome.