Gene: FCN1

Alternate names for this Gene: FCNM

Gene Summary: The ficolin family of proteins are characterized by the presence of a leader peptide, a short N-terminal segment, followed by a collagen-like region, and a C-terminal fibrinogen-like domain. The collagen-like and the fibrinogen-like domains are also found separately in other proteins such as complement protein C1q, C-type lectins known as collectins, and tenascins. However, all these proteins recognize different targets, and are functionally distinct. Ficolin 1 encoded by FCN1 is predominantly expressed in the peripheral blood leukocytes, and has been postulated to function as a plasma protein with elastin-binding activity.

Gene is located in Chromosome: 9

Location in Chromosome : 9q34.3

Description of this Gene: ficolin 1

Type of Gene: protein-coding

rs10117466 in FCN1 gene and Blood Protein Measurement PMID 29875488 2018 Genomic atlas of the human plasma proteome.