Gene: FOXP4

Alternate names for this Gene: hFKHLA

Gene Summary: This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Many members of the forkhead box gene family, including members of subfamily P, have roles in mammalian oncogenesis. This gene may play a role in the development of tumors of the kidney and larynx. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms.

Gene is located in Chromosome: 6

Location in Chromosome : 6p21.1

Description of this Gene: forkhead box P4

Type of Gene: protein-coding

rs1983891 in FOXP4 gene and Malignant neoplasm of prostate PMID 20676098 2010 Genome-wide association study identifies five new susceptibility loci for prostate cancer in the Japanese population.

rs1983891 in FOXP4 gene and Prostate carcinoma PMID 20676098 2010 Genome-wide association study identifies five new susceptibility loci for prostate cancer in the Japanese population.

PMID 31562322 2019 12 new susceptibility loci for prostate cancer identified by genome-wide association study in Japanese population.

rs3800283 in FOXP4 gene and mathematical ability PMID 30038396 2018 Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.