Gene: GNL3

Alternate names for this Gene: C77032|E2IG3|NNP47|NS

Gene Summary: The protein encoded by this gene may interact with p53 and may be involved in tumorigenesis. The encoded protein also appears to be important for stem cell proliferation. This protein is found in both the nucleus and nucleolus. Three transcript variants encoding two different isoforms have been found for this gene.

Gene is located in Chromosome: 3

Location in Chromosome : 3p21.1

Description of this Gene: G protein nucleolar 3

Type of Gene: protein-coding

Gene: PBRM1

Alternate names for this Gene: BAF180|PB1

Gene Summary: This locus encodes a subunit of ATP-dependent chromatin-remodeling complexes. The encoded protein has been identified as in integral component of complexes necessary for ligand-dependent transcriptional activation by nuclear hormone receptors. Mutations at this locus have been associated with primary clear cell renal cell carcinoma.

Gene is located in Chromosome: 3

Location in Chromosome : 3p21.1

Description of this Gene: polybromo 1

Type of Gene: protein-coding

rs1108842 in GNL3;PBRM1 gene and Adiponectin Measurement PMID 22479202 2012 Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.

rs565817433 in GNL3;PBRM1 gene and Body Fat Distribution PMID 30664634 2019 Genome-wide association study of body fat distribution identifies adiposity loci and sex-specific genetic effects.

rs1108842 in GNL3;PBRM1 gene and Intelligence PMID 29326435 2019 A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.

rs10933 in GNL3;PBRM1 gene and Waist-Hip Ratio PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.