Gene: GSTP1

Alternate names for this Gene: DFN7|FAEES3|GST3|GSTP|HEL-S-22|PI

Gene Summary: Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. This GST family member is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases.

Gene is located in Chromosome: 11

Location in Chromosome : 11q13.2

Description of this Gene: glutathione S-transferase pi 1

Type of Gene: protein-coding

rs1695 in GSTP1 gene and Blood Protein Measurement PMID 29875488 2018 Genomic atlas of the human plasma proteome.

rs1871042 in GSTP1 gene and Corpuscular Hemoglobin Concentration Mean PMID 23222517 2012 Seventy-five genetic loci influencing the human red blood cell.