Gene: H2AC15

Alternate names for this Gene: H2A.1|H2A/d|H2AC11|H2AC13|H2AC14|H2AC16|H2AC17|H2AFD|HIST1H2AK

Gene Summary: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3.

Gene is located in Chromosome: 6

Location in Chromosome : 6p22.1

Description of this Gene: H2A clustered histone 15

Type of Gene: protein-coding

Gene: H2BC15

Alternate names for this Gene: H2B/d|H2BFD|HIST1H2BN

Gene Summary: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3.

Gene is located in Chromosome: 6

Location in Chromosome : 6p22.1

Description of this Gene: H2B clustered histone 15

Type of Gene: protein-coding

rs13212651 in H2AC15;H2BC15 gene and Intelligence PMID 29326435 2019 A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.

rs34706883 in H2AC15;H2BC15 gene and Schizophrenia PMID 26198764 2015 Genome-wide association study of schizophrenia in Ashkenazi Jews.