Gene: HELQ

Alternate names for this Gene: HEL308

Gene Summary: HEL308 is a single-stranded DNA-dependent ATPase and DNA helicase (Marini and Wood, 2002 [PubMed 11751861]).[supplied by OMIM, Mar 2008].

Gene is located in Chromosome: 4

Location in Chromosome : 4q21.23

Description of this Gene: helicase, POLQ like

Type of Gene: protein-coding

rs4693089 in HELQ gene and Age at menarche PMID 29773799 2018 Elucidating the genetic architecture of reproductive ageing in the Japanese population.

rs4693089 in HELQ gene and Age at menopause PMID 22267201 2012 Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways.

PMID 26414677 2015 Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair.

PMID 29773799 2018 Elucidating the genetic architecture of reproductive ageing in the Japanese population.

rs1494961 in HELQ gene and Head and Neck Neoplasms PMID 21437268 2011 A genome-wide association study of upper aerodigestive tract cancers conducted within the INHANCE consortium.