Gene: HK2

Alternate names for this Gene: HKII|HXK2

Gene Summary: Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.

Gene is located in Chromosome: 2

Location in Chromosome : 2p12

Description of this Gene: hexokinase 2

Type of Gene: protein-coding

rs1869340 in HK2 gene and Schizophrenia PMID 21926974 2011 Genome-wide association study identifies five new schizophrenia loci.