Gene: HPN

Alternate names for this Gene: TMPRSS1

Gene Summary: This gene encodes a type II transmembrane serine protease that may be involved in diverse cellular functions, including blood coagulation and the maintenance of cell morphology. Expression of the encoded protein is associated with the growth and progression of cancers, particularly prostate cancer. The protein is cleaved into a catalytic serine protease chain and a non-catalytic scavenger receptor cysteine-rich chain, which associate via a single disulfide bond. Alternative splicing results in multiple transcript variants.

Gene is located in Chromosome: 19

Location in Chromosome : 19q13.11

Description of this Gene: hepsin

Type of Gene: protein-coding

Gene: HPN-AS1

Alternate names for this Gene:

Gene Summary:

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rs2452000 in HPN;HPN-AS1 gene and Body Height PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.