Gene: HSPB7

Alternate names for this Gene: cvHSP

Gene Summary: This gene encodes a small heat shock family B member that can heterodimerize with similar heat shock proteins. Defects in this gene are associated with advanced heart failure. In addition, the encoded protein may be a tumor suppressor in the p53 pathway, with defects in this gene being associated with renal cell carcinoma.

Gene is located in Chromosome: 1

Location in Chromosome : 1p36.13

Description of this Gene: heat shock protein family B (small) member 7

Type of Gene: protein-coding

rs1572381 in HSPB7 gene and Body Height PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs1739843 in HSPB7 gene and Cardiomyopathy, Dilated PMID 20975947 2010 Genetic association study identifies HSPB7 as a risk gene for idiopathic dilated cardiomyopathy.

rs1048238 in HSPB7 gene and Systolic Pressure PMID 28739976 2017 Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney.