Gene: IFNAR1

Alternate names for this Gene: AVP|IFN-alpha-REC|IFNAR|IFNBR|IFRC

Gene Summary: The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The protein belongs to the type II cytokine receptor family and functions as an antiviral factor.

Gene is located in Chromosome: 21

Location in Chromosome : 21q22.11

Description of this Gene: interferon alpha and beta receptor subunit 1

Type of Gene: protein-coding

rs2257167 in IFNAR1 gene and Blood Protein Measurement PMID 29875488 2018 Genomic atlas of the human plasma proteome.

PMID 30072576 2018 Co-regulatory networks of human serum proteins link genetics to disease.

rs17875833 in IFNAR1 gene and Serum total cholesterol measurement PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.

rs17875833 in IFNAR1 gene and Triglycerides measurement PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.