Gene: IL1RL2

Alternate names for this Gene: IL-1Rrp2|IL-36R|IL1R-rp2|IL1RRP2

Gene Summary: The protein encoded by this gene is a member of the interleukin 1 receptor family. An experiment with transient gene expression demonstrated that this receptor was incapable of binding to interleukin 1 alpha and interleukin 1 beta with high affinity. This gene and four other interleukin 1 receptor family genes, including interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2), interleukin 1 receptor-like 1 (IL1RL1), and interleukin 18 receptor 1 (IL18R1), form a cytokine receptor gene cluster in a region mapped to chromosome 2q12.

Gene is located in Chromosome: 2

Location in Chromosome : 2q12.1

Description of this Gene: interleukin 1 receptor like 2

Type of Gene: protein-coding

rs10167431 in IL1RL2 gene and Allergic Reaction PMID 23817569 2013 A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci.

rs1997502 in IL1RL2 gene and Eosinophil count procedure PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs185815317 in IL1RL2 gene and Squamous cell carcinoma of lung PMID 29924316 2018 Genome-wide association study of familial lung cancer.