Gene: ITGB5

Alternate names for this Gene: -

Gene Summary: This gene encodes a beta subunit of integrin, which can combine with different alpha chains to form a variety of integrin heterodimers. Integrins are integral cell-surface receptors that participate in cell adhesion as well as cell-surface mediated signaling. The alphav beta5 integrin is involved in adhesion to vitronectin.

Gene is located in Chromosome: 3

Location in Chromosome : 3q21.2

Description of this Gene: integrin subunit beta 5

Type of Gene: protein-coding

rs9875516 in ITGB5 gene and Body Height PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs4141663 in ITGB5 gene and Diastolic blood pressure PMID 27841878 2017 Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.

rs7373878 in ITGB5 gene and Major Depressive Disorder PMID 22915352 2012 Dissecting the genetic heterogeneity of depression through age at onset.

rs11928547 in ITGB5 gene and Systolic Pressure PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

PMID 30578418 2019 Trans-ethnic association study of blood pressure determinants in over 750,000 individuals.

PMID 27841878 2017 Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.