Gene: JARID2

Alternate names for this Gene: JMJ

Gene Summary: This gene encodes a Jumonji- and AT-rich interaction domain (ARID)-domain-containing protein. The encoded protein is a DNA-binding protein that functions as a transcriptional repressor. This protein interacts with the Polycomb repressive complex 2 (PRC2) which plays an essential role in regulating gene expression during embryonic development. This protein facilitates the recruitment of the PRC2 complex to target genes. Alternate splicing results in multiple transcript variants. Mutations in this gene are associated with chronic myeloid malignancies.

Gene is located in Chromosome: 6

Location in Chromosome : 6p22.3

Description of this Gene: jumonji and AT-rich interaction domain containing 2

Type of Gene: protein-coding