Gene: KCNJ15

Alternate names for this Gene: IRKK|KIR1.3|KIR4.2

Gene Summary: Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Eight transcript variants encoding the same protein have been found for this gene.

Gene is located in Chromosome: 21

Location in Chromosome : 21q22.13-q22.2

Description of this Gene: potassium inwardly rectifying channel subfamily J member 15

Type of Gene: protein-coding

rs2065306 in KCNJ15 gene and Leukemia, Myelocytic, Acute PMID 27903959 2017 Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.

rs2836179 in KCNJ15 gene and Waist-Hip Ratio PMID 30575882 2018 Association of Genetic Variants Related to Gluteofemoral vs Abdominal Fat Distribution With Type 2 Diabetes, Coronary Disease, and Cardiovascular Risk Factors.