Gene: KCNK5

Alternate names for this Gene: K2p5.1|KCNK5b|TASK-2|TASK2

Gene Summary: This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The message for this gene is mainly expressed in the cortical distal tubules and collecting ducts of the kidney. The protein is highly sensitive to external pH and this, in combination with its expression pattern, suggests it may play an important role in renal potassium transport.

Gene is located in Chromosome: 6

Location in Chromosome : 6p21.2

Description of this Gene: potassium two pore domain channel subfamily K member 5

Type of Gene: protein-coding

rs2815116 in KCNK5 gene and Body Height PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs10947789 in KCNK5 gene and CORONARY ARTERY DISEASE, AUTOSOMAL DOMINANT, 1 PMID 23202125 2013 Large-scale association analysis identifies new risk loci for coronary artery disease.

rs10456100 in KCNK5 gene and Coronary Artery Disease PMID 29212778 2018 Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.

PMID 23202125 2013 Large-scale association analysis identifies new risk loci for coronary artery disease.

rs10456100 in KCNK5 gene and Migraine Disorders PMID 27322543 2016 Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine.

PMID 23793025 2013 Genome-wide meta-analysis identifies new susceptibility loci for migraine.

PMID 27182965 2016 Detection and interpretation of shared genetic influences on 42 human traits.