Gene: KCNMB2-AS1

Alternate names for this Gene:

Gene Summary:

Gene is located in Chromosome:

Location in Chromosome :

Description of this Gene:

Type of Gene:

Gene: KCNMB2

Alternate names for this Gene: -

Gene Summary: MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which decreases the activation time of MaxiK alpha subunit currents. Alternative splicing results in multiple transcript variants of this gene. Additional variants are discussed in the literature, but their full length nature has not been described.

Gene is located in Chromosome: 3

Location in Chromosome : 3q26.32

Description of this Gene: potassium calcium-activated channel subfamily M regulatory beta subunit 2

Type of Gene: protein-coding

rs13100616 in KCNMB2-AS1;KCNMB2 gene and AMYOTROPHIC LATERAL SCLEROSIS 1 PMID 24529757 2014 Genome-wide association study combining pathway analysis for typical sporadic amyotrophic lateral sclerosis in Chinese Han populations.

rs13100616 in KCNMB2-AS1;KCNMB2 gene and AMYOTROPHIC LATERAL SCLEROSIS 1, AUTOSOMAL RECESSIVE PMID 24529757 2014 Genome-wide association study combining pathway analysis for typical sporadic amyotrophic lateral sclerosis in Chinese Han populations.

rs13100616 in KCNMB2-AS1;KCNMB2 gene and AMYOTROPHIC LATERAL SCLEROSIS 6 (disorder) PMID 24529757 2014 Genome-wide association study combining pathway analysis for typical sporadic amyotrophic lateral sclerosis in Chinese Han populations.

rs13100616 in KCNMB2-AS1;KCNMB2 gene and Amyotrophic Lateral Sclerosis, Sporadic PMID 24529757 2014 Genome-wide association study combining pathway analysis for typical sporadic amyotrophic lateral sclerosis in Chinese Han populations.

rs2054399 in KCNMB2-AS1;KCNMB2 gene and Bipolar Disorder PMID 22688191 2012 Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder.

rs2054399 in KCNMB2-AS1;KCNMB2 gene and Mental disorders PMID 22688191 2012 Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder.

rs2054399 in KCNMB2-AS1;KCNMB2 gene and Psychotic Disorders PMID 22688191 2012 Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder.

rs2054399 in KCNMB2-AS1;KCNMB2 gene and Schizophrenia PMID 22688191 2012 Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder.

rs61606793 in KCNMB2-AS1;KCNMB2 gene and Suicide attempt PMID 30145303 2018 A genome-wide association study of suicide attempts and suicidal ideation in U.S. military veterans.

rs115510347 in KCNMB2-AS1;KCNMB2 gene and response to ACE inhibitor PMID 28084903 2017 Genetic variants associated with angiotensin-converting enzyme inhibitor-induced cough: a genome-wide association study in a Swedish population.