Gene: KCNMB4

Alternate names for this Gene: -

Gene Summary: MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which slows activation kinetics, leads to steeper calcium sensitivity, and shifts the voltage range of current activation to more negative potentials than does the beta 1 subunit.

Gene is located in Chromosome: 12

Location in Chromosome : 12q15

Description of this Gene: potassium calcium-activated channel subfamily M regulatory beta subunit 4

Type of Gene: protein-coding

rs394571 in KCNMB4 gene and Body Height PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.